Immune Health

Dosage:

• Adults: 1 g daily as an ongoing maintenance dose, or 3 to 4 g daily at the onset of symptoms and for the duration of illness
  
• Children: 1 to 2 g daily as an ongoing maintenance dose
  

Benefits:

• Reduces the duration of the common cold by approximately a half-day, or by 8% in adults and by 14-18% in children
• Reduces time of confinement by approximately six hours
• Reduce fever duration by approximately a half-day,
• Relieves chest pain and chills by approximately eight hours when given an extra therapeutic dose at the time of onset of cold
• Decreases duration of cold by 59%
  

Dosage:

• 400 mg, once per day, minimum 8-16 weeks in healthy adults as a preventative measure
  

Benefits:

• Reduces the duration of colds or acute respiratory infections by approximately 5-6 days
• Reduces the incidence of colds and influenza and respiratory syncytial virus
• Reduces total symptom severity score for sore throat, runny nose, sneezing, nasal congestion, malaise, fever, headache, hoarseness, earaches, and cough
  

Dosage:

• Prevention: 0.9 mL, three times per day (equivalent to 2400 mg of extract), minimum 4 months
• Acute: Up to 4.5 mL liquid extract (equivalent to 4000 mg), once per day at the first stage of cold development
  

Benefits:

• Reduces the relative risk of cold development 
• Reduces the incidence of cumulative viral infections and recurring infections by including influenza virus and parainfluenza virus
  

Dosage:

• 75-100 mg of elemental zinc as zinc acetate or zinc gluconate lozenges, once per day, within 24 hours of the onset of common cold symptoms, minimum 1 to 2 weeks cold

Benefits:

• Reduces cold duration 
• Reduces the incidence of cold symptoms after 5-7 days in healthy adults and children
• Reduces the duration of muscle soreness, cough, voice hoarseness, nasal congestion, nasal discharge, scratchy throat, sneezing, and sore throat by in healthy adults
• Reduces the incidence of common cold development, absence from school, and antibiotic use in children
• Reduces duration of symptoms particularly when given within the first 24 hours of symptom onset
  

Probiotics may reduce the incidence of colds with minor effects on prevention, as well as improve influenza vaccination efficacy for A/H1N1, A/H3N2, and B strains, but is dependent on strain and population.

Common Cold

• 5 billion CFU of Lactobacillus acidophilus NCFM (ATCC 700396), twice per day, minimum 6 months
• Benefits:
• Reduces the incidence of fever, cough, and antibiotic use
• Reduces the duration of fever, coughing, and rhinorrhea
• Reduces days absent from childcare 
  

Influenza (Flu)

• 10 billion CFU of Bifidobacterium animalis subs. lactis Bi-07 (ATCC PTA-4802) & Lactobacillus acidophilus NCFM (ATCC 700396), twice per day for 6 months
• Benefits:
• Reduces the incidence of fever, rhinorrhea, cough, and antibiotic
• Reduces the duration of fever, coughing, and rhinorrhea 
• Reduces days absent from childcare
  

Adult:

Common Cold

• 1 billion CFU of Lactobacillus paracasei 8700:2 (DSM 13434) & Lactobacillus plantarum HEAL 9 (DSM 15312), once per day for 3 months
• Benefits:
• Reduces the incidence of developing more than one common cold episode and number of days with a cold
• Reduces total symptom scores & pharyngeal symptoms of cold
• Reduces B lymphocyte proliferation
  

Influenza (Flu)

• 10 billion CFU of Lactobacillus fermentum CECT5716, once per day for 2 weeks before influenza vaccination and two weeks after
• Benefits:
• Reduces the incidence of influenza 5-months after vaccination compared to vaccine alone
• Increases natural killer cells, T-helper response, and IgA levels
  

• 10 billion CFU of Lactobacillus rhamnosus GG, twice per day for 4 weeks after influenza vaccination
  
• Benefits:
• Increases seroprotection for the H3N2 strain during the supplementation period
  

• 500 mg of Saccharomyces cerevisiae (EpiCor®), once per day for 12 weeks
  
• Benefits:
• Reduces the incidence of cold/flu symptoms with or without prior vaccination
• Reduces the duration of symptoms with prior vaccination